Education plays a vital role in ensuring the progress and development of a nation. A perfect education system should be able to transform an individual into a successful citizen, and at the same time receive the blessings of the Almighty. Malaysia’s National Education Philosophy had outlined the importance of implementing integrated principles to nurture individuals that are at peace with one’s physical, emotional, spiritual and intelectual aspects. For muslim students, what is meant by the implementation of integrated principles are the infused and fortified of school subjects with the teachings of the holy Quran and as-sunnah. This study attempts to determine students’ readiness to learn science within religous sociocultural context. A total of 74 Form Two muslim students responded to questionnaires on Perception Towards Science-Religion Interaction (PTSR) and Attitude Towards Science (ATS). The findings indicated that students hold positive PTSR. There is also exist an average correlation between PTSR and ATS (r= 0.334).